Regional dynamics of amyloid-b deposition in healthy elderly, mild cognitive impairment and Alzheimer’s disease: a voxelwise PiB–PET longitudinal study
نویسندگان
چکیده
Regional dynamics of amyloid-b deposition in healthy elderly, mild cognitive impairment and Alzheimer’s disease: a voxelwise PiB–PET longitudinal study Nicolas Villain, Gaël Chételat, Blandine Grassiot, Pierrick Bourgeat, Gareth Jones, Kathryn A. Ellis, David Ames, Ralph N. Martins, Francis Eustache, Olivier Salvado, Colin L. Masters, Christopher C. Rowe, Victor L. Villemagne and the AIBL Research Group*
منابع مشابه
Regional dynamics of amyloid-β deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: a voxelwise PiB-PET longitudinal study.
Amyloid-β deposition in Alzheimer's disease is thought to start while individuals are still cognitively unimpaired and it is hypothesized that after an early phase of fast accumulation, a plateau is reached by the time of cognitive decline. However, few longitudinal Pittsburgh compound B-positron emission tomography studies have tested this hypothesis, and with conflicting results. The purpose ...
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